Baclofen Tablets –Treatment of muscle spasms and stiffness caused by spasticity and/or muscle weakness in patients with cerebral palsy
Baclofen tablets contain a combination of baclofen and a non-narcotic non-antispasmodic anti-spastic agent (NAC) which helps reduce muscle spasticity and stiffness in patients with cerebral palsy. Baclofen is used in combination with paracetamol for the management of spasticity of the cerebral cortex, legs and other muscles in adults and adolescents over the age of 12 years. Paracetamol is used in combination with baclofen to treat muscle spasticity and stiffness in adults and adolescents over the age of 12 years. For more information visit:
Adults and adolescents and children over 12 years: 1 tablet daily for 7 days or more, in the form of a syrup, with the recommended dose depending on the severity and nature of the muscle spasticity and stiffness. The dose can be adjusted up to 6 hours before or 6 hours after your dose of baclofen.
Do not exceed the recommended dose.
Consult your doctor if your condition does not improve or if it worsens
Do not use in case of hypersensitivity to baclofen or any of its components.
Each tablet contains:
If you are allergic to baclofen or paracetamol and have a history of muscle spasticity, you should not take baclofen Tablets. Contact your doctor or pharmacist immediately if you develop muscle spasms or pain during or following activities such as: sudden loss of vision, hearing loss, muscle weakness, tightness or painful swallowing, sudden or irregular heartbeat; sudden or severe dizziness; chest pain; shortness of breath; fainting; or during the first few months of treatment. This may cause temporary or permanent sleepiness, anxiety, irritability, depression, psychosis or ataxia. Avoid drinking alcohol as it may make you more sensitive to the side effects of baclofen.
If you are pregnant, or breast-feeding, or you are taking other products containing baclofen, or if you have a history of muscle spasticity, you should use caution while you are taking baclofen Tablets. Avoid consuming alcohol as it may make you more sensitive to baclofen.
This is not a complete list of adverse reactions. If you notice any other signs or symptoms of health changes, unusual weakness or discomfort, or if they occur, report the signs or symptoms with your doctor or pharmacist as well as the negative effects of the product on your child or if you are worried about the signs or symptoms.
Do not drive, operate machinery, or do anything that should prevent you from doing anything yourself that requires assistance.
Avoid eating or drinking anything that contains alcohol or alcohol to avoid nausea.
If you experience any of the following signs or symptoms: swelling of your feet or lower legs, call your doctor immediately or get emergency medical treatment: pain in your lower legs, fever, chills, cough, shortness of breath, skin rash with or without fever, unusual tiredness, difficulty in breathing, increased thirst, poor or poor-smelling urine, vomiting or diarrhea. Drinking alcohol while you are taking baclofen may cause excessive alcohol consumption which may be harmful for your unborn child or your infant.
If you experience any of the following signs or symptoms: anxiety, trouble concentrating, confusion, trouble or pain in your arms, neck, stomach or pelvis, change in sense of taste or smell, rapid speech, trouble speaking, sore or tender breasts, large or small breasts, a fast heartbeat, or sudden loss of appetite, contact your doctor or pharmacist if you have an increased risk of passing baclofen.
Consult your doctor or pharmacist if you experience a change in appetite, especially if you have trouble swallowing.
Baclofen (Neurobiotics) can be purchased by calling +1-888-704-0408 and talking with a customer service representative, or by placing an online order at liferxpharmacy.com. Customer Support is also aided by using the chat feature. For additional information, visit the "How to Order" page on liferxpharmacy.com.
Baclofen (Neurobiotics) is a medication that can only be purchased with a doctors prescription. While processing your order for the medication, it is necessary to get a valid prescription from your doctor The prescription can be scanned, emailed, or uploaded at liferxpharmacy.com or fax on +1-800-986-4751 Alternatively, if you like, we can even contact your doctor to obtain a valid prescription.
The maximum amount of Baclofen (Neurobiotics) can be ordered at one time is a 90-day supply. The amount that can be ordered is dependent on the instructions and quantity mentioned on your medical prescription. Refilling alternate is always available for future needs.
It is a completely safe and secure choice to order your medicine from us. We function similarly alike any other traditional pharmacy, intending to serve safe and affordable prescription medicines. Our associated pharmacists are functional in many countries and are completely licensed and certified.
Baclofen (Neurobiotics) is available in both generic and brand form. Generic medicines contain the same active components as brand-name pharmaceuticals have. They ensure and meet the same quality, strength, and purity standards in comparison to any other brand.
Yes. We deliver all around the United States and other major countries.
LifeRx pharmacy makes it simple to refill your medication. By going to your accounts reorder section, you can easily place a refill option available online. You may examine your prior orders and choose which prescriptions order needs to be refilled. To order a refill, you can also call us and chat with one of our customer service representatives. Our live chat is also one of the convenient ways to reach out to us while placing a refill order.
We do not automatically refill prescriptions as it might be the case where you may no longer be taking the same medicines or your doctor may have revised your dose, among other things. However, we do offer a helpful refill reminder service. Based on your prescription history, we may call or email you to let you know when the ideal time is to place a refill order.
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After completing theATTENTION: The effects of Baclofen (Neurobiotics) may take up to 6 weeks to start working.
Generic name:Baclofen pump - pump type
PMS-0104-09 - BACLOFEN is used to relieve muscle spasms caused by various conditions, including spasticity of the spine and other muscles, spasms due to multiple sclerosis, cerebral palsy, and spinal cord injuries. BACLOFEN is also used to treat moderate spasticity (muscle pain) in adults and children aged 4 years and older.
BACLOFEN is a medicine containing SODH (sulfites in the formulation of baclofen). It contains three salts (Baclofen, D-Spongiform Carcinoma, and SODH2).
The recommended dose is one BACLOFEN pump pump each day, depending on the severity of the condition being treated. Your doctor will decide the appropriate dosage based on the severity of your condition and on the condition being treated.
The treatment may take 1-2 weeks to fully kick in, and in some cases may last for 3-4 weeks.
If you are taking another medicine (e.g. alpha-blockers, antifungals), it is recommended to consult your doctor for a copy of this information.
If you are taking baclofen for muscle spasms, your doctor may advise you to take one BACLOFEN pump pump every day for the treatment period.
The treatment is most effective when taken with food, preferably 30 minutes before the procedure. If you are having surgery, it is recommended to take one BACLOFEN pump pump every day.
Do not exceed the recommended dose.
The pump should be refilled after each pump pump refill date.
If there are any problems with your pump, contact your doctor or pharmacist for advice.
BACLOFEN is not for use in children.
BACLOFEN is not for use by pregnant women, or children under 4 years old.
BACLOFEN may be used for purposes not listed in this medication guide.
Information on baclofen is provided on the website of the American Academy of Neurology (AAAN). This medication is not intended to diagnose, treat, cure, or prevent any disease or medical condition.
PMS0104-09 - BACLOFEN is used to relieve muscle spasms caused by various conditions, including spasticity of the spine and other muscles, spasms due to multiple sclerosis, cerebral palsy, and spinal cord injuries.PMS0104-09 - BACLOFEN is used to relieve muscle spasms due to multiple sclerosis, cerebral palsy, and spinal cord injuries.
Baclofen, a nonsteroidal anti-inflammatory drug, is widely recognized for its efficacy in managing neurological conditions such as multiple sclerosis, spinal cord injuries, and cerebral palsy. Its key components, including baclofen, are primarily metabolized by the cytochrome P450 (CYP) system, and they are mainly metabolized by CYP2C9, CYP3A4, and CYP2D6. Baclofen is widely used in the medical field, with its extensive use, particularly in muscle disorders, due to its ability to alleviate pain and inflammation and to increase muscle mass. This review provides an analysis of the efficacy of baclofen for the management of muscle spasticity and pain associated with multiple sclerosis, spinal cord injuries, cerebral palsy, and other neurological conditions.
Baclofen is a highly selective inhibitor of the CYP3A4 and CYP2C9 enzymes, and its metabolism is mainly mediated through CYP2D6. The main active metabolite of baclofen, 4-chloro-baclofen (3-(4-chloro-5-methyl-1,3-dihydro-1-methylbenzamide)-1,3-dihydro-3-(4-methyl-1,5-pyrimidinyl)-1,5-heptadeca-1-ene-17-carboxamide), has been identified as a potent inhibitor of CYP3A4. Inhibition of CYP3A4 leads to increased plasma concentrations of the active metabolite, which are primarily metabolized by CYP2C9, CYP2D6, and CYP1A2. These metabolites are metabolized by CYP2D6 to become active and inhibit the enzyme CYP2D6 in the presence of endogenous substances. Thus, inhibition of these enzymes leads to decreased plasma concentrations of the active metabolite, and ultimately to inhibition of the metabolism of baclofen.
Inhibition of CYP2C9 and CYP3A4 leads to increased plasma concentrations of the active metabolite, which are primarily metabolized by CYP2D6 to become active and inhibit the enzyme CYP2D6 in the presence of endogenous substances. Inhibition of CYP3A4 leads to decreased plasma concentrations of the active metabolite, which are primarily metabolized by CYP2C9 to become active and inhibit the enzyme CYP2C8 in the presence of endogenous substances. Thus, inhibition of the enzymes CYP2C9 and CYP3A4 leads to decreased plasma concentrations of the active metabolite, and ultimately to inhibition of the metabolism of baclofen.
Baclofen has been used off-label for muscle spasticity treatment, primarily in the medical field. In muscle spasticity, baclofen has shown promise in the treatment of multiple sclerosis, spinal cord injuries, cerebral palsy, and other neurological disorders. Studies have shown that baclofen can effectively alleviate pain, improve quality of life, and improve function. However, the underlying mechanisms remain unclear. This review discusses the effectiveness of baclofen in managing muscle spasticity and discusses its potential applications in other therapeutic areas.
Baclofen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used to treat musculoskeletal conditions such as multiple sclerosis, spinal cord injuries, cerebral palsy, and other neurological disorders. Baclofen has demonstrated efficacy in alleviating spasticity and improving quality of life, and its use has also been reported to improve function and quality of life in patients with multiple sclerosis and cerebral palsy.
Baclofen has shown promising results in muscle spasticity management in several clinical studies. A review of randomized controlled trials (RCTs) found that baclofen was a highly effective and well-tolerated treatment for muscle spasticity. However, it has also been associated with several adverse effects, including gastrointestinal disturbances, rhabdomyolysis, and neutropenia. In addition, baclofen has been associated with hepatotoxicity and cardiopulmonary toxicity in rheumatoid arthritis patients. Therefore, the efficacy of baclofen in muscle spasticity has not been assessed.
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